BEAUTY RESTORATION

Dermatology and cosmetology are a special area of ​​work of International Biotherapy Institute. Using natural ingredients, we develop and put into practice dermatological new cosmetics with unsurpassed efficiency. We partner with leading dermatologists and cosmetologists to create unique skin healing programs.

In recent years, dermatology schools have focused on the problem of acne in adult women. Adult female blackheads (adult female acne) are defined as affecting women over 25 and may occur continuously or intermittently for a prolonged period, up to and including menopause. Genetic and hormonal factors are thought to contribute to the development of acne in adulthood. The disease is long-lasting, relapsing and requires systemic treatment, very often for many years. [1-4]

Adult female acne is a topical and complex therapeutic problem because they tend to relapse even after repeated cycles of antibiotics, hormonal contraceptives, anti-androgens and isotretinoin. [5,6]

The difficulties and setbacks in acne therapy have inspired specialists at the International Institute of Biotherapy to find new effective and safe treatments for this disease. Anti-recurrent immunocorrection using natural peptides - defensins and RJP - has shown remarkable results.

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Anti-relapse immunocorrection in acne. By destroying the infectious component and ensuring scar-free healing, a harmonious skin recovery is ensured.

 

Defensins inhibit reproduction and destroy propionibacteria, which is a key of infectious component of acne. [7-9] Due to its powerful anti-inflammatory effect and facilitated regeneration, RJP-1 ensures timely and harmonious healing of acne defects. [10-12].

After the use of peptides, pronounced inhibition of the activity of propionibacteria in the skin occurs, and at the site of acne, an optimal regenerative effect is achieved. The use of anti-relapse immunocorrection to treat acne restores and maintains local immunity in the skin.

 Complete skin recovery without ulcers and unwanted scars is the desired result, which can be achieved by anti-recurrent immunocorrection. After all, it is extremely important for a woman to be not only healthy but also beautiful. Because her beauty adorns the world.

 

  1. Cong TX, Hao D, Wen X, Li XH, He G, Jiang X. From pathogenesis of acne vulgaris to anti-acne agents. Arch Dermatol Res. 2019;311(5):337–349.

  2. Woo TE, Sibley CD. The emerging utility of the cutaneous microbiome in the treatment of acne and atopic dermatitis. J Am Acad Dermatol. 2020;82(1):222–228.

  3. Dréno B, Thiboutot D, Layton AM, Berson D, Perez M, Kang S, Global Alliance to Improve Outcomes in Acne Large-scale international study enhances understanding of an emerging acne population: adult females. J Eur Acad Dermatol Venereol. 2015;29:1096–1106.

  4. Dréno B. Treatment of adult female acne: a new challenge. J Eur Acad Dermatol Venereol. 2015;29(Suppl 5):14–19.

  5. Holzmann R, Shakery K. Postadolescent acne in females. Skin Pharmacol Physiol. 2014;27(Suppl 1):S3–S8.

  6. Hazarika N. Acne vulgaris: new evidence in pathogenesis and future modalities of treatment. J Dermatolog Treat. 2019;1–33.

  7. Gómez DM, Lone YC, Salazar LM, Trojan J (2019) Antimicrobial peptides, novel solution for the treatment of precancerous disease acne - A review. Trends Med 19: DOI: 10.15761/TiM.1000210

  8. Brandwein, Michael et al. “Endogenous Antimicrobial Peptide Expression in Response to Bacterial Epidermal Colonization.” Frontiers in immunology vol. 8 1637. 27 Nov. 2017, doi:10.3389/fimmu.2017.01637

  9. Mohiuddin Ak (2019) A Comprehensive Review of Acne Vulgaris. J Clin Pharm Vol: 1, Issue: 1 (17-45).

  10. Siavash M, Shokri S, Haghighi S, Mohammadi M, Shahtalebi MA, Farajzadehgan Z. The efficacy of topical Royal Jelly on diabetic foot ulcers healing: A case series. J Res Med Sci. 2011;16(7):904–909.

  11. Lin Y, Shao Q, Zhang M, Lu C, Fleming J, Su S. Royal jelly-derived proteins enhance proliferation and migration of human epidermal keratinocytes in an in vitro scratch wound model. BMC Complement Altern Med. 2019;19(1):175. Published 2019 Jul 12. doi:10.1186/s12906-019-2592-7.

  12. Tian, W., Li, M., Guo, H. et al. Architecture of the native major royal jelly protein 1 oligomer. Nat Commun 9, 3373 (2018). 

 

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